Spore, Cell Stage, and GIANTmicrobes
 

First of all, Spore is a game that allows you to evolve through many stages of evolution or just create. Cell Stage might be fun for Microbe Fans, it's like an open-area Pac-Man. Some Pictures:
http://www.techshout.com/images/spor...screenshot.jpghttp://forums.electronicarts.co.uk/i...mp_jpgcopy.jpghttp://images.bit-tech.net/content_i...preview/b3.jpghttp://buttonmasher.co.nz/wp-content...09/spore02.jpg
For the creators, here are some microbes that should be familiar to you:
http://www.spore.com/sporepedia#qry=...LONY%3Afl-NONE